Synthesis, In Vitro and In Silico biological studies of 1, 2, 3-triazole-furan chalcone hybrids

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dc.contributor.author Somanatha, T. M.
dc.contributor.author Krishnaswamy, G.
dc.contributor.author Bhavana, R.
dc.contributor.author Radhakrishna, K.
dc.contributor.author Shivaraj, G.
dc.contributor.author Sreenivasa, S.
dc.contributor.author Shet, Prakash M.
dc.coverage.spatial India
dc.date.accessioned 2023-11-17T15:22:12Z
dc.date.available 2023-11-17T15:22:12Z
dc.date.issued 2023-09
dc.identifier.citation Somanatha, T. M.; Krishnaswamy, G.; Bhavana, R.; Radhakrishna, K.; Shivaraj, G.; Sreenivasa, S. and Shet, Prakash M., "Synthesis, In Vitro and In Silico biological studies of 1, 2, 3-triazole-furan chalcone hybrids", Indian Journal of Heterocyclic Chemistry, DOI: 10.59467/IJHC.2023.33.369, vol. 33, no. 3, pp. 369-375, Sep. 2023.
dc.identifier.issn 0971-1627
dc.identifier.uri https://doi.org/10.59467/IJHC.2023.33.369
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/9462
dc.description.abstract In the present investigation, we focused our interest to develop 1, 2, 3-triazolefuran chalcone hybrids along with their biological profile. The synthesis of target molecules involves sequence of reactions, namely diazotization, nucleophilic substitution, cycloaddition and finally, solvent-free Claisen-Schmidt condensation reaction. The biological profile of the synthesized compounds was carried out using prediction of activity spectra for substances and results revealed that the synthesized compounds may act as mild antimicrobial agents.
dc.description.statementofresponsibility by T. M. Somanatha, G. Krishnaswamy, R. Bhavana, K. Radhakrishna, G. Shivaraj, S. Sreenivasa and Prakash M. Shet
dc.format.extent vol. 33, no. 3, pp. 369-375
dc.language.iso en_US
dc.publisher Connect Journals
dc.subject 1, 2, 3-Triazole
dc.subject Aromatic azides
dc.subject Chalcones
dc.subject Prediction of activity spectra for substances and biological profile
dc.subject Substituted furaldehyde
dc.title Synthesis, In Vitro and In Silico biological studies of 1, 2, 3-triazole-furan chalcone hybrids
dc.type Article
dc.relation.journal Indian Journal of Heterocyclic Chemistry


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