• Thiazolyl Benzenesulfonamide derivative as a novel inhibitor of Thymidine Kinase: promising therapeutics against staphylococcus aureus 

  Hadiya, Rajesh K.; Ashraf, Anam; Wang, Yuanyuan; Khan, Faez Iqbal; Khan, Mohammad Ali; Renuka, L.; Ahmad, Shahbaz; Noor, Saba; Shah, Kaushik; Datta, Bhaskar; Hassan, Md. Imtaiyaz (Wiley, 2025-07)

  The emergence of multidrug-resistant Staphylococcus aureus necessitates novel antimicrobial strategies. This study reports the synthesis and evaluation of thiazolyl benzenesulfonamide-derived synthetic kinase inhibitors ...
• Nucleobase self-assembly: aggregation, morphological characterization, and toxicity analysis 

  Dave, Raj; Jaiswal, Ankita; Singh, Ankur; Naseer, Anam; Patel, Monisha; Nazir, Aamir; Bhatia, Dhiraj; Gour, Nidhi; Verma, Sandeep (Royal Society of Chemistry, 2025-06)

  This study expands the platform for amyloidogenic building blocks, such as nucleobases, and their self-assembly. Here, we examine the self-assembly profile of nucleobases such as guanine, cytosine, and thymine and determine ...
• Impact of chlorine substitution on supramolecular architecture and non-covalent interactions in Ethyl 2-amino-6-chloro-4-aryl-7-hydroxy-4H-benzo[4,5-e]pyran-3-carboxylate Isomers: a combined experimental, crystallographic, theoretical, and antioxidant study 

  Jebaraj, Paul Daniel; Purushothaman, Michael; Loganathan, Karuppiah; Percino, M. Judith; Thiruvenkatam, Vijay; Venkatesan, Perumal (Springer, 2025-07)

  Two positional isomers, ethyl 2-amino-6-chloro-4-(2-chlorophenyl)-7-hydroxy-4H-benzo-[4,5-e]pyran-3-carboxylate (1) and ethyl 2-amino-6-chloro-4-(3-chlorophenyl)-7-hydroxy-4H-benzo- [4,5-e] pyran-3-carboxylate (2) were ...
• Chemically engineered multifunctional hydrogel for potential use in biomedical applications: a report on synthesis, physicochemical characterizations, and in vitro evaluation 

  Barani, Prasanna Kumari; Yadav, Indu; Dan, Aniruddha; Singh, Ankur; Bhatia, Dhiraj; Dhanka, Mukesh (Elsevier, 2025-10)

  Addressing the limitations of conventional polymeric hydrogels in eradicating bacterial infection and stimulating cell activity within a biological environment presents a significant challenge. However, chemically engineered ...
• Upcycling fruit waste: a sustainable route to nanoparticles synthesis and applications 

  Bhalerao, Satyam; Patil, Jugal; Bhatia, Dhiraj; Singh, Nihal (American Chemical Society, 2025-07)

  Fruits are a common part of a healthy human diet as they are rich in vitamins, minerals, antioxidants, dietary fibers, and flavor. However, the processing and subsequent consumption of fruits result in a significant amount ...
• Shear-induced structural changes drive amorphous aggregate formation of human insulin 

  Panda, Chinmaya; Kumar, Sachin; Gupta, Sharad; Pandey, Lalit M. (Wiley, 2025-06)

  The aggregation of protein-based biopharmaceutical formulations constitutes a major challenge in the pharmaceutical industry, where physicochemical stressors, viz., temperature, pH, shear, and high concentrations, ...
• Splice it right: the role of PRP21 in regulating seed germination responses to ABA 

  Gawande, Nilesh D. (Oxford University Press, 2025-06)
• 3D printed metamaterials: properties, fabrication, and drug delivery applications 

  Singh, Hemant; Tuffaha, Muath; Tripathi, Shivi; Öztürk, Ayça Bal; Dave, Harshil; Dhanka, Mukesh; Avci, Huseyin; Nanda, Himansu Sekhar; Hassan, Shabir (Elsevier, 2025-09)

  Drug delivery is a process to deliver the required amount of a drug to a target site within an appropriate timeframe, while minimizing possible side effects and maximizing efficiency. This is accomplished by drug delivery ...
• Putative G-Quadruplex structures in dysregulated long non-coding RNA of Ovarian Cancer and their binding interactions with human serum Albumin 

  Singh, Deepshikha; Shukla, Chinmayee; Datta, Bhaskar (American Chemical Society, 2025-06)

  Long noncoding RNAs (lncRNAs) influence the progression, metastasis, and drug resistance of various cancers including ovarian cancer (OC). Putative G-quadruplex (G4)-forming sequences that are abundant in cancer-dysregulated ...
• Zingerone nanoparticle and laponite-embedded natural gum based injectable hydrogel for fast track wound repair 

  Meena, Manisha; Yadav, Indu; Barani, Prasanna Kumari; Gajjar, Devanshi; Joshi, Aneri; Seshadri, Sriram; Dhanka, Mukesh (Elsevier, 2025-11)

  Currently, the treatment modalities for hard-to-heal deep skin wounds are limited by bacterial growth, excessive wound exudate, elevated reactive oxygen species (ROS), and extensive tissue damage. This study reports a ...
• ROS regulation of stigma papillae growth and maturation in Arabidopsis thaliana 

  Sankaranarayanan, Subramanian; Venkatesan, Sowmiya D.; Davis, Thomas C.; Kessler, Sharon A. (Springer, 2025-06)

  Highly specialized stigma papillae cells play a critical role in plant reproduction. Their main purpose is to catch and interact with pollen, to mediate compatibility responses, to regulate pollen germination, and to guide ...
• Injectable self-healing dynamic aldehyde-gellan gum-based hydrogel nanocomposite with enhanced antibacterial and antioxidant wound dressing to alleviate chronic skin wound 

  Dan, Aniruddha; Singh, Hemant; Shah, Tishira K.; Sheikh, Wajid Mohammad; Shafi, Majid; Laxmanan, Karthikeyan; Jan, Jasmeena; Hassan, Shabir; Bashir, Showkeen Muzamil; Dhanka, Mukesh (Elsevier, 2025-08)

  The difficult-to-heal wounds present a significant challenge for current treatment modalities due to factors such as impaired tissue microenvironments, disrupted inflammatory balance, impaired cellular proliferation, and ...
• Engineering a bacterial polysaccharide-based metal-organic framework-enhanced bioactive 3D hydrogel for accelerated full-thickness wound healing 

  Dan, Aniruddha; Panigrahi, Ankita; Singh, Hemant; Murali, Varsha; Meena, Manisha; Goyal, Prateek; Laxmanan, Karthikeyan; Misra, Superb K.; Varghese, Nibu; Babu, Sharlene Sara; Dalvi, Yogesh B.; Dhanka, Mukesh (Royal Society of Chemistry, 2025-05)

  Hydrogels offer numerous advantages in wound healing, making them a promising alternative to traditional wound dressings. Their biocompatibility and high water content closely resemble natural biological tissues, creating ...
• DNA nano-biomaterials based futuristic technologies for tissue engineering and regenerative therapeutics 

  Kansara, Krupa; Mansuri, Abdulkhalik; Kumar, Ashutosh; Bhatia, Dhiraj (Wiley, 2025-06)

  The ability to completely repair or regenerate injured tissues or organs and restore their functionality has long been a goal of humankind. The advancements in tissue engineering and regenerative medicine have made this ...
• Structurally interlinked multi-crosslinking bioactive hydrogel network with enhanced antioxidant, antibiofilm, and antibacterial functionalities 

  Laxmanan, Karthikeyan; Yadav, Indu; Barani, Prasanna Kumari; Meena, Manisha; Kang, Hyun Wook; Dhanka, Mukesh (Elsevier, 2025-06)

  Recent advances in designing effective multifunctional hydrogel materials have attracted remarkable attention for their biomedical applications, particularly in controlled drug delivery, regenerative medicine, antibiofilm, ...
• REV-ERBβ Binding Pocket Dynamics With Implications for Rational Design of Small Molecule Modulators 

  Srivastava, Shriyansh; A. M., Vishnu; Thakur, Rakesh; Srivastava, Ashutosh (Wiley, 2025-05)

  REV-ERBβ is a nuclear receptor (NR) with heme as an endogenous ligand that regulates its transcriptional activity. With a key role in cellular functions such as glucose metabolism, immune response, and dysregulation in ...
• A functional 2D MXene-DNA hybrid hydrogel for portable detection of blood disorder biomarker thrombin in human plasma 

  Morya, Vinod; Bhatia, Dhiraj; Ghoroi, Chinmay; Yadav, Amit K. (Royal Society of Chemistry, 2025-05)

  Delaminated MXenes (2D MXenes) and DNA hydrogels have created enormous opportunities due to their versatility and ability to be tailored for specific applications. 2D MXenes offer high aspect ratio morphology and electrical ...
• Sequestration of Acrylamide as Amino Acid-Acrylamide adducts mitigates cellular stress in human gastrointestinal cell lines 

  Patel, Axita; Datta, Bhaskar (Royal Society of Chemistry, 2025-05)

  Acrylamide (ACR) is a global health concern in starchy and cereal-based heat-processed foods. While amino acids (AA) have been suggested as effective scavengers of acrylamide, there is a dearth of information about the ...
• Multifaceted Roles of U-Box E3 Ligases in Plant Development 

  Karthik, H. N.; Parmar, Sourabh; Gawande, Nilesh D.; Sankaranarayanan, Subramanian (Oxford Univeristy Press, 2025-05)

  Post-translational modifications (PTMs) are crucial for providing plants with the metabolic flexibility needed to regulate cellular signaling during development and stress responses. Ubiquitination, a key PTM, is mediated ...
• Neurotransmitter-Loaded DNA Nanocages as Potential Therapeutics for α-Synuclein-Based Neuropathies in Cells and In Vivo 

  Vaswani, Payal; Kosra, Sanjay; Kansara, Krupa; Kumar, Ashutosh; Bhatia, Dhiraj (American Chemical Society, 2025-06)

  Parkinson’s disease is one of the neuropathies characterized by accumulation of the α-synuclein protein, leading to motor dysfunction. Levodopa is the gold standard treatment; however, in long-term usage, it leads to ...

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