| dc.contributor.author |
Jain, Sweny |
|
| dc.contributor.author |
Sahu, Nidhi |
|
| dc.contributor.author |
Bhatia, Dhiraj |
|
| dc.contributor.author |
Yadav, Pankaj |
|
| dc.coverage.spatial |
United Kingdom |
|
| dc.date.accessioned |
2024-09-04T10:52:36Z |
|
| dc.date.available |
2024-09-04T10:52:36Z |
|
| dc.date.issued |
2024-08 |
|
| dc.identifier.citation |
Jain, Sweny; Sahu, Nidhi; Bhatia, Dhiraj and Yadav, Pankaj, "Cellular uptake and viability switching in the properties of lipid coated carbon quantum dots for potential bioimaging and therapeutics", Nanoscale Advances, DOI: 10.1039/D4NA00306C, Aug. 2024. |
|
| dc.identifier.issn |
2516-0230 |
|
| dc.identifier.uri |
https://doi.org/10.1039/D4NA00306C |
|
| dc.identifier.uri |
https://repository.iitgn.ac.in/handle/123456789/10391 |
|
| dc.description.abstract |
Carbon quantum dots derived from mango leaves exhibited red fluorescence. These negatively charged particles underwent coating with the positively charged lipid molecule N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA). However, the bioconjugate displayed reduced uptake compared to the standalone mQDs in cancer cells (SUM 159A), and increased uptake in case of non-cancerous (RPE-1) cells. Upon in vitro testing, the bioconjugate demonstrated a mitigating effect on the individual toxicity of both DOTMA and mQDs in SUM-159 (cancerous cells). Conversely, it exhibited a proliferative effect on RPE-1 (normal cells). |
|
| dc.description.statementofresponsibility |
by Sweny Jain, Nidhi Sahu, Dhiraj Bhatia and Pankaj Yadav |
|
| dc.language.iso |
en_US |
|
| dc.publisher |
Royal Society of Chemistry |
|
| dc.title |
Cellular uptake and viability switching in the properties of lipid coated carbon quantum dots for potential bioimaging and therapeutics |
|
| dc.type |
Article |
|
| dc.relation.journal |
Nanoscale Advances |
|