Nanomaterials for delivery of medicinal plant extracts and phytochemicals: potential applications and future perspectives

Abstract

Nature has been an immense reservoir of therapeutic agents derived from medicinal plants. Bioactive compounds isolated from these plants have demonstrated significant pharmacological potential across a range of medical applications, including cancer therapy, cardiovascular and neuroprotective effects, antimicrobial activity, wound healing, and anti-inflammatory effects. Despite their remarkable therapeutic potential, the clinical translation of these phytochemicals is restricted by challenges such as poor solubility, limited stability, and non-specific distribution. Recent advancements in nanotechnology have revolutionized their delivery by addressing these limitations. Nano-based approaches for delivery of medicinal plant extracts and phytochemicals have emerged as promising strategies in the development of advanced drug delivery systems. This review presents a comprehensive overview of recent progress in nanomaterial-mediated delivery of medicinal plant extracts and phytochemicals, highlighting their transformative potential in overcoming traditional limitations and addressing complex therapeutic needs in modern healthcare.