Live-cell imaging of the nucleolus and mapping mitochondrial viscosity with a dual function fluorescent probe

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dc.contributor.author Mukherjee, Tarushyam
dc.contributor.author Soppina, Virupakshi
dc.contributor.author Ludovic, Richert
dc.contributor.author Mely, Yves
dc.contributor.author Klymchenko, Andrey S.
dc.contributor.author Collot, Mayeul
dc.contributor.author Kanvah, Sriram
dc.coverage.spatial United Kingdom
dc.date.accessioned 2021-02-22T13:54:21Z
dc.date.available 2021-02-22T13:54:21Z
dc.date.issued 2021-01
dc.identifier.citation Mukherjee, Tarushyam; Soppina, Virupakshi; Ludovic, Richert; Mely, Yves; Klymchenko, Andrey S.; Collot, Mayeul and Kanvah, Sriram, “Live-cell imaging of the nucleolus and mapping mitochondrial viscosity with a dual function fluorescent probe”, Organic & Biomolecular Chemistry, DOI: 10.1039/D0OB02378G, vol. 19, no. 15, pp. 3389-3395, Jan. 2021. (Cover Page) en_US
dc.identifier.issn 1477-0520
dc.identifier.issn 1477-0539
dc.identifier.uri https://doi.org/10.1039/D0OB02378G
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/6307
dc.description.abstract Visualization of sub-cellular organelles allows the determination of various cellular processes and the underlying mechanisms. Herein, we report a fluorescent probe, bearing push–pull substituents emitting at 600 nm and its application in cellular imaging. The probe shows dual imaging of mitochondria and nucleoli and maps mitochondrial viscosity in live cells under various physiological variations and show minimum cytotoxicity. Nucleolar staining is confirmed by RNAase digestion.
dc.description.statementofresponsibility by Tarushyam Mukherjee, Virupakshi Soppina, Richert Ludovic, Yves Mely, Andrey S. Klymchenko, Mayeul Collot and Sriram Kanvah
dc.format.extent vol. 19, no. 15, pp. 3389-3395
dc.language.iso en_US en_US
dc.publisher Royal Society of Chemistry en_US
dc.subject Live-cell en_US
dc.subject Mapping en_US
dc.subject Nucleolar staining en_US
dc.title Live-cell imaging of the nucleolus and mapping mitochondrial viscosity with a dual function fluorescent probe en_US
dc.type Article en_US
dc.relation.journal Organic and Biomolecular Chemistry


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